Masivukeni, which translates to 'Let's wake up!' in the Xhosa language, is a computer-supported curriculum designed to help patients in South Africa stay on their antiretroviral medication. Masivukeni provides lay counselors with an intervention roadmap and scripts that help them communicate to their patients the importance of adherence to treatment plans. In addition, the Masivukeni tool features interactive activities to help patients build their support network, develop problem-solving skills, visualize their pill regimen, and learn how HIVaffects the body as viral resistance develops.