The Hand-Drawn Look
See the concept above? Using Topaz Adjust and Akvis Sketch, you can make photos look like they were drawn by hand. It's certainly not perfect, but it can often result in something interesting and, dare I say it, "artsy." (The picture frames came from a free stock photo website.)
Step 1: Duplicate the original layer.
Step 2: Select the duplicate layer and go to Filter -> Topaz Labs -> Topaz Adjust -> HDR Collection -> Dynamic Pop 1 or 2 (your choice).
Step 3: Duplicate the layer from step 2 and go to Filter -> Topaz Labs -> Topaz Adjust -> Vibrant Collection -> Detail Strong 1 or 2 (your choice).
Step 4: Duplicate the original layer and go to Filter -> AKVIS -> Sketch. I use the default settings.
Step 5: When you return to Photoshop, select the hard light blend mode for the sketch layer and reduce its opacity. I usually do 75%.
Step 6: Duplicate the later from step 3 and move it to the top of the layer stack. Reduce its opacity to whatever you like!