The Pennsylvanian is a 444-mile (715 km) daytime Amtrak train running between New York and Pittsburgh via Philadelphia. The trains travel across the Appalachian Mountains, through Pennsylvania's capital Harrisburg, the Pennsylvania Dutch Country, suburban and central Philadelphia, and New Jersey en route to New York. Trains run once daily in each direction. The entire train ride takes about 9 hours total, with 1.5 hours between New York and Philadelphia, 2 hours between Philadelphia and Harrisburg, and 5.5 hours between Harrisburg and Pittsburgh.[2]

Scenic highlights include:
• Pittsburgh's Golden Triangle, the place where the Allegheny, Monongahela and Ohio Rivers converge
• The Allegheny Mountains
• The famous Horseshoe Curve near Altoona, PA
• Pennsylvania Dutch Country

The Pennsylvanian is a once a day replacement of the Keystone service between New York and Pittsburgh, offering Business Class seating as an upgrade to the coach-only seating on Keystone trains. Prior to Amtrak, the route was known as the Duquesne, named after Fort Duquesne in Pittsburgh, and operated by the Pennsylvania Railroad. The Pennsylvanian began on April 27, 1980, as a state-supported daylight train between Philadelphia and Pittsburgh, with connecting service to New York. Amtrak would later extend the train to serve New York directly. Between November, 1998 and January, 2003, Amtrak shifted the endpoints west to Chicago and Philadelphia, providing daylight service to Cleveland, Ohio. In 2003 the Pennsylvanian reverted to a Pittsburgh–New York schedule. On its inauguration the Pennsylvanian used Amfleet equipment and continues to be so equipped.