To mark World Children’s Day, a new study by researchers from the International Agency for Research on Cancer (IARC) and partners, published today in Nature Medicine, estimates the number of maternal orphans due to cancer in 2020, globally and in 185 countries and territories. These new estimates, which were also presented in a flash talk at the World Cancer Congress 2022 last month, suggest that as a result of the estimated 4.4 million women who died from cancer in 2020, about 1 million children became maternal orphans in that year.