COVER ART FOR BICYCLE THERAPEUTICS
commissioned work
A fully synthetic and tumor-targeted immune cell agonist, consisting of three bicyclic peptides connected via a branched PEG linker cross-links Nectin-4 on a tumor cell and CD137 on immune cells, resulting in tumor-localized immune agonism.
article:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00505
