My version of "The Lady with an Ermine" (1489–1491) by the master Leonardo da Vinci.
The original work is painted in oils on a panel of walnut wood. The lady is Cecilia Gallerani, a mistress of Ludovico Sforza, Duke of Milan.
As for my take on it, I did my version of Cecilia Gallerani holding my cat, Calvin, on her lap. Pixels on a panel of glass and circuits =D.