Promoters are specific DNA sequences located upstream open reading frames. These sequences are recognized by DNA-binding proteins called "transcription factors". The function of the transcription factors is the proper recruitment of the transcription machinery to the promoter (RNA polymerase and other accessory proteins), being essential for gene expression regulation. Here you can see a human Zinc-finger DNA-binding transcription factor, ZBTB7A, bound to the promoter of the fetal beta globin gene. The structure was determined by X-ray diffraction at a moderate resolution (PDB code: 7NST)
#molecularart ... #immolecular ... #transcription ... #promoter ... #DNAbinding ... #Znfinger ... #TF ... #Xray ... Rendered with @proteinimaging and finished with @corelphotopaint
#molecularart ... #immolecular ... #transcription ... #promoter ... #DNAbinding ... #Znfinger ... #TF ... #Xray ... Rendered with @proteinimaging and finished with @corelphotopaint
