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Heterochromia

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  • In anatomy, heterochromia refers to a difference in coloration, usually of the iris but also of hair or skin. Heterochromia is a result of the relative excess or lack of melanin (a pigment). It may be inherited, or caused by genetic mosaicism, disease, or injury. [1]
    Heterochromia of the eye (heterochromia iridis or heterochromia iridum; the common wrong form "heterochromia iridium" is not correct Latin) is of two kinds. In complete heterochromia, one iris is a different color from the other. In partial heterochromia or sectoral heterochromia, part of one iris is a different color from its remainder.
    Eye color, specifically the color of the irises, is determined primarily by the concentration and distribution of melanin. [2] [3] [4] The affected eye may be hyperpigmented (hyperchromic) or hypopigmented (hypochromic). [5] In humans, usually, an excess of melanin indicates hyperplasia of the iris tissues, whereas a lack of melanin indicates hypoplasia.
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