Hi,
I run Cubase 4.1, TC Powercore MK2 (DSP Card with Dope plugin's), Battery, Kontakt and Absynth 4 and the albino.
I use cubase 4.1 because I have been a Cubase user since SX 1, I find the work Flow fast and it does eveything I need and it runs on both mac and pc.
I love the native instruments instruments battery and kontakt are amazing for manipulating samples and Absynth is a beast at creating evolving synth patchs and atmospheres.
And teh powercore is a must for teh high end system 6000 reverbs
Try this program its free and open source
http://reaper.fm/
I have used it edit audio for the economists audio magazine when I was still a student. Its pretty good and free! should be a good place to learn the basics and have a play around!
Hope that helps a bit
Lewis